Leaky cells and the use of Lactobacillus casei in the treatment of laboratory animals infected with amoebic dysentery

Abstract EN

In the present study, a total of 45 Albino Sprague-Dawley rats were suffered from watery diarrhoea were examined.

All samples of feces had Entamoeba histolytica.

The studied rats were divided into three groups ; the first one was gave orally 2 ml of Lactobacillus casei extraction, the second was gave 2 ml of L.

casei suspension, and the third was gave 2 ml of normal saline as positive control.

The 1st group was appeared 12 / 15 (80 %) of recovery, the 2nd group appeared 15 / 15(100 %) of recovery, and the 3rd group appeared no recovery 0 / 15 (0.0).

Also two ml of vein Blood was collected from rats to determine hemoglobin level (Hb), packed cell volume (PCV), Red Blood Cells Count, and white blood cells differential (WBC's differential).

Our results showed that the means of RBC's count (4.7, 5.8, 4.5, 4.7)x 106 / mm3, Hb levels (12.26, 14.77, 12.54, 13.2) gm / dl and PCV values (37.8, 42.1, 36.9, 37.6) % for control, infected, treatment with L.casei extract and treatment with L.casei suspension groups, respectively.

Also there were rise in numbers of lymphocytes, monocytes and eosinophils significantly, and decline in the ratio of types heterophils and basophils.

This study concluded that the use of L.

casei is useful in the treatment of diarrhea caused by amoebic dysentery parasite.