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The impact of inflammation on resistin, IL-6 and CRP in acute myocardial infarction patients
Joint Authors
al-Yasin, Hadif Zafir
Ibrahim, Amal E.
al-Janabi, Hamid K. Sashit
Source
Journal of the Faculty of Medicine Baghdad
Issue
Vol. 53, Issue 2 (30 Jun. 2011), pp.216-220, 5 p.
Publisher
University of Baghdad Faculty of Medicine
Publication Date
2011-06-30
Country of Publication
Iraq
No. of Pages
5
Main Subjects
Topics
Abstract EN
Background: Inflammation contributes across the spectrum of cardiovascular disease, including the earliest steps in atherogenesis.
Myocardial Infarction (MI) is most commonly due to occlusion (blockage) of a coronary artery following the rupture of a vulnerable atherosclerotic plaque.
It has been suggested that the adipose tissue may play an important role in mediating this chronic inflammatory process, human resistin, is a 12.5-kDa protein, it found in the inflammatory zone.
Interleukin-6 (IL-6) is a pro-inflammatory cytokine, it secreted by T cells and macrophages to stimulate immune response.
C-reactive protein (CRP) is a protein found in the blood, the levels of CRP rise in response to inflammation.
Objective: to determine the role of Resistin in Acute myocardial infarction patients and its effects on IL-6 and CRP.
Patients and Methods : The study included 50 patients with Acute Myocardial Infarction and 40 healthy subject as control, levels of resistin, Interleukin-6 (IL-6) and CRP were measured.
Results: The levels of resistin, IL-6 and CRP were significantly elevated with (p < 0.001).
There was positive correlation between resistin with IL-6 and CRP in acute myocardial infarction patients.
Conclusions : There was significantly increasing in levels of resistin, in acute myocardial infarction patients and this increasing may be related to inflammation.
Resistin positively correlated with proinflammatory factor (IL-6 and CRP) so it have inflammation properties may consider a cardiovascular risk factor.
American Psychological Association (APA)
Ibrahim, Amal E.& al-Yasin, Hadif Zafir& al-Janabi, Hamid K. Sashit. 2011. The impact of inflammation on resistin, IL-6 and CRP in acute myocardial infarction patients. Journal of the Faculty of Medicine Baghdad،Vol. 53, no. 2, pp.216-220.
https://search.emarefa.net/detail/BIM-334961
Modern Language Association (MLA)
Ibrahim, Amal E.…[et al.]. The impact of inflammation on resistin, IL-6 and CRP in acute myocardial infarction patients. Journal of the Faculty of Medicine Baghdad Vol. 53, no. 2 (2011), pp.216-220.
https://search.emarefa.net/detail/BIM-334961
American Medical Association (AMA)
Ibrahim, Amal E.& al-Yasin, Hadif Zafir& al-Janabi, Hamid K. Sashit. The impact of inflammation on resistin, IL-6 and CRP in acute myocardial infarction patients. Journal of the Faculty of Medicine Baghdad. 2011. Vol. 53, no. 2, pp.216-220.
https://search.emarefa.net/detail/BIM-334961
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 219-220
Record ID
BIM-334961