Factor V leiden mutation in Iraqi patients with deep venous thrombosis
Joint Authors
Jubrail, Jaladat M. S.
Hilmi, Firyal A.
al-Allawi, Nasir
Source
Journal of the Faculty of Medicine Baghdad
Issue
Vol. 53, Issue 3 (30 Sep. 2011), pp.293-295, 3 p.
Publisher
University of Baghdad Faculty of Medicine
Publication Date
2011-09-30
Country of Publication
Iraq
No. of Pages
3
Main Subjects
Topics
Abstract EN
Background : Factor V Leiden is considered the most common inherited risk factor for venous thrombosis in Caucasian populations, including those in the Eastern Mediterranean region.
While several studies have addressed Factor V Leiden prevalence in patients with venous thrombosis in the Eastern Mediterranean countries, none have been reported from Iraq.
Objective : To study the prevalence of Factor V Leiden in an unselected group of Iraqi patients with Deep Venous thrombosis.
Materials and Methods : A total of 50 unselected patients with deep venous thrombosis referred to the Medical City Teaching Hospital in Baghdad, Iraq, as well as 40 age and sex matched controls, were enrolled.
The evaluation included in addition to detailed history, Factor V Leiden by polymerase Chain reaction and reverse hybridization.
Results : Factor V Leiden mutation was documented in 8 patients (16 %), compared to 1 control (2.5 %) (Odds Ratio 7.4; p = 0.0397).
The mutation was more frequent among younger patients, those with family history of thrombosis and those with recurrent thrombosis, but only the latter was of significance.
Conclusions : The study suggests that Factor V Leiden is frequently encountered in Iraqi patients with Deep venous thrombosis from Baghdad, but less so than in some surrounding Eastern Mediterranean countries.
Although further larger studies maybe warranted, the current study favors screening for Factor V Leiden in the workup of newly diagnosed venous thrombosis cases in this city.
American Psychological Association (APA)
al-Allawi, Nasir& Jubrail, Jaladat M. S.& Hilmi, Firyal A.. 2011. Factor V leiden mutation in Iraqi patients with deep venous thrombosis. Journal of the Faculty of Medicine Baghdad،Vol. 53, no. 3, pp.293-295.
https://search.emarefa.net/detail/BIM-335157
Modern Language Association (MLA)
Jubrail, Jaladat M. S.…[et al.]. Factor V leiden mutation in Iraqi patients with deep venous thrombosis. Journal of the Faculty of Medicine Baghdad Vol. 53, no. 3 (2011), pp.293-295.
https://search.emarefa.net/detail/BIM-335157
American Medical Association (AMA)
al-Allawi, Nasir& Jubrail, Jaladat M. S.& Hilmi, Firyal A.. Factor V leiden mutation in Iraqi patients with deep venous thrombosis. Journal of the Faculty of Medicine Baghdad. 2011. Vol. 53, no. 3, pp.293-295.
https://search.emarefa.net/detail/BIM-335157
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 295
Record ID
BIM-335157