The effect of taurine on reproductive efficiency in male rats fed high cholesterol diet

Abstract EN

The study designed to use high cholesterol diet to male rats(Rattus norvegicus) and asses the ability of the different concentrations of taurine to protect the reproduction from the harmful effect of hypercholesterolemia during 4 weeks of treatment .Thirty six adult male rats were used, randomly divided into six equal groups (six for each)as control and five treatment groups.

Control of animals were fed on the standard ration.

First treated group was supplied with the standard ration in addition to 1.5 % taurine .

Second treated group was supplied with standard ration in addition to 1.5 % cholesterol .Third, Fourth and Fifth treated groups were supplied with standard ration in addition to 1.5 % cholesterol and 2, 3and 4 % taurine / kg ration respectively and were handled for four weeks.

At the end of the experiment the blood serum samples were collect and FSH, LH, testosterone and estrogen levels were taken and sperm vitality was recorded in addition to the weight of testis and epididymis were recorded.

The results revealed to the positive role of taurine in protection of reproductive from the pad effect of hypercholesterolemia in male rats .The taurine led to increase in Gonadotropin hormones FSH and LH in addition to the testosterone after it has been reduced due to cholesterol in the ration and as a results to gonadotropin and testosterone hormone improvement ,the sperm viability was improved as well after it was decline due to high cholesterol addition in experimental diet .