Leptin effects on, thyroid hormones and some biochemical parameters of female rabbits (lepus cuniculus)‎ serum

Abstract EN

Thirty local female rabbits were divided randomly and equally into three groups.

The 1st group used as control which injected with phosphate buffer salin.

The 2nd group was injected daily with leptin (5μg / animal) S / c.

The 3rd group was injected subcutaneously daily with (10μg / animal) S / c.

All groups were treated for 60 days, and blood samples were collected every 15 days, serum was tested for T3, T4 hormones, total Cholesterol (TC), HDL (height density lipo-protein), LDL (low density lipo- protein), TG (triglycerides) and Body weight was taken every 15 days during the experiment . The result show significant (P ≤ 0.05) decreased in body weight after administration of leptin in two doses.

Significant increased in Thyroid hormone after leptin administration.

While lipid profile (TC, TG, LDL, HDL,VLDL) show significant decreased with leptin treatment (5 and 10μg / animal) S / c.