The frequency of thyroid carcinoma in patients with solitary and multiple nodules utilizing ultrasound guided fine needle aspiration cytology (FNAC) : a prospective study (thyroid carcinoma and U S guided FNA)
Joint Authors
Kazim, Muhammad A.
Ahmad, Basim S.
Mahdi, Qahtan A.
Source
Journal of the Faculty of Medicine Baghdad
Issue
Vol. 52, Issue 2 (30 Jun. 2010), pp.134-138, 5 p.
Publisher
University of Baghdad Faculty of Medicine
Publication Date
2010-06-30
Country of Publication
Iraq
No. of Pages
5
Main Subjects
Topics
Abstract EN
Background : Population studies suggest that 3–8 % of asymptomatic adults have thyroid nodules.
Nodules have a 5–15 % prevalence of malignancy.
Fine-needle aspiration cytology is the primary and frequently initial tool for assessing the risk of malignancy in thyroid nodules and selecting patients for thyroid surgery.
Patients and Methods : This prospective study was done during the period from June 2007 to November 2008.
The study includes 141 patients with palpable solitary or multiple thyroid nodules.
Only patients with normal or low TSH values were referred for ultrasound examination and ultrasound guided FNAC, which were done using fine needles (G 20).
Results : eleven patients (7.8 %) have insufficient or non-diagnostic aspirates and were excluded from the study.
Of the remaining 130 patients that were included in our study, only 20 patients had thyroid carcinoma (15.3 %).
Seventy-nine patients (60.7 %) had solitary nodule larger than 10 mm in largest dimension and 51 patients (39.3 %) had two or more such nodules.
The rate of cancer in males with thyroid nodules was higher than in females.
The prevalence of thyroid cancer did not differ between patients with a solitary thyroid nodule (12 of 79 patients, 15.1 %) and patients with multiple nodules (8 of 51 patients, 15.7 %), the deference is statistically insignificant (P = 0.95).
A nodule that is one of several nodules had a lower likelihood of being malignant than did a solitary nodule : (8.9 % versus 15.1 %) (P < 0.001).
Conclusion : Ultrasound guided FNAC is the primary and frequently initial tool for assessing the risk of malignancy in thyroid nodules.
The prevalence of thyroid cancer did not differ between patients with a solitary thyroid nodule and those with multiple thyroid nodules.
FNAC have limited role in cytological diagnosis of follicular carcinomas, unless it is confirmed by histopathological diagnosis.
American Psychological Association (APA)
Kazim, Muhammad A.& Ahmad, Basim S.& Mahdi, Qahtan A.. 2010. The frequency of thyroid carcinoma in patients with solitary and multiple nodules utilizing ultrasound guided fine needle aspiration cytology (FNAC) : a prospective study (thyroid carcinoma and U S guided FNA). Journal of the Faculty of Medicine Baghdad،Vol. 52, no. 2, pp.134-138.
https://search.emarefa.net/detail/BIM-335761
Modern Language Association (MLA)
Mahdi, Qahtan A.…[et al.]. The frequency of thyroid carcinoma in patients with solitary and multiple nodules utilizing ultrasound guided fine needle aspiration cytology (FNAC) : a prospective study (thyroid carcinoma and U S guided FNA). Journal of the Faculty of Medicine Baghdad Vol. 52, no. 2 (2010), pp.134-138.
https://search.emarefa.net/detail/BIM-335761
American Medical Association (AMA)
Kazim, Muhammad A.& Ahmad, Basim S.& Mahdi, Qahtan A.. The frequency of thyroid carcinoma in patients with solitary and multiple nodules utilizing ultrasound guided fine needle aspiration cytology (FNAC) : a prospective study (thyroid carcinoma and U S guided FNA). Journal of the Faculty of Medicine Baghdad. 2010. Vol. 52, no. 2, pp.134-138.
https://search.emarefa.net/detail/BIM-335761
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 137-138
Record ID
BIM-335761