The possible association between chlamydia pneumonia infection and asthma

Abstract EN

Background : Many etiological factors have been implicated in the pathogenesis of Asthma like ; viruses, bacteria and Chlamydia pneumoniae.

This study focuses on the role of Chlamydia pneumoniae in asthma pathogenesis.

Patients and Methods : The detection of Anti-Chlamydia pneumoniae antibodies IgA, IgM and IgG in patients by ELISA, for 35 patients, 18 asthmatic patients, 12 patients with chest infection with no history of asthma, and 5 apparently healthy as control subjects.

Results : The results showed that 80 % and 70 % of the patients were negative for anti- Chlamydia pneumonia antibodies IgA and IgM respectively, while significantly (p < 0.05) high number (73 %) of patients were positive for IgG, of which significant number (p < 0.05) of them, 63 % were asthmatic and 36 % were non-asthmatic chest infection.

Conclusion : this study may support the association between Chlamydia pneumoniae and asthma.