In vivo study of cherry stick effect on concentration of serum total cholesterol, triglyceride and total protein in white albino male mice

Abstract EN

Background : Cherry extract has a wide range of biological activity.

In the present investigation, two oral doses 0.04 and 0.08 mg / kg / day of cherry stick (ethanol extract) in albino male mice resulted in a significant decrease in concentration of serum total cholesterol concentration, triglyceride and total protein, albumin and globulin.

Objective : we investigated the impact of biological activities of cherry stick extract on serum cholesterol, triglyceride, total protein, albumin and globulin in white albino male mice.

Design : This study include three groups of white albino male mice.

The first group (G1) was a control group comprised of 5 animals.

The second group (G2) consisted of 5 animals treated with 1ml of cherry stick extract at concentration of 0.04 mg / kg / day for two weeks after treatment, while the third group (G3) consists of 5 animals treated with 1ml of cherry stick extract at concentration of 0.08 mg / kg / day for two weeks with treated animals.

Results : there was a statistically significant reducing effect on serum total cholesterol, triglyceride, total protein and albumin P < 0.001 at 0.04 mg / kg / day and 0.08 mg / kg / day for all biochemical parameters.

Globulin was markedly decreased P < 0.01 in comparison with control but no significant change in ratio of albumin to globulin.

Conclusion : Extract of cherry stick exerts at low dose a remarkable effect on serum cholesterol, triglyceride and total protein.