Comparison between the effect of propofol (TIVA)‎ and inhalational anesthesia (halothane)‎ on early postoperative nausea and vomiting

Abstract EN

Background : postoperative nausea and vomiting (PONV) is a highly observed feature postoperatively.

The type of surgery, the technique, medication, duration of anesthesia, and various patient factors all contribute to the condition.

Objectives : to evaluate and compare the effect of halothane and propofol on early postoperative nausea and vomiting.

Patients and methods : A randomized clinical trial was conducted on 80 patients who scheduled for hernioplasty during the 1st of October / 2010 to the 5th of February / 2012 in Baghdad Teaching Hospital / Medical City Complex / Baghdad / Iraq.

All patients were allocated into two groups randomly (40 patients each), group(A) were received 1-2 mg / Kg propofol as induction and used for maintenance of anesthesia and group (B) were receive anesthetizing dose of thiopentone 3-5 Mg / Kg, and maintained on halothane.

Presence of nausea and vomiting episodes were recorded at 4 time schedule (recovery, 2 hours, 4 hours and 6 hours) postoperatively in both groups.

Result: the incidence of nausea and vomiting were more among cases who received halothane, and along the time from recovery to 6 hours post operatively nausea and vomiting were absent in all cases of propofol group.

Conclusion : early PONV is less with propofol based anesthesia than with inhalational based anesthesia.