Detection of mycoplasma hominis and ureaplasma urealyticum in blood samples of recurrent pregnancy loss in women by polymerase chain reaction

Abstract EN

Background : Genital mycoplasma are implicated in pelvic inflammatory disease, puerperal infection, septic abortion, low birth weight, nongonococcal urethritis and prostatitis as well as spontaneous abortion and infertility in women.

Objective : We aimed to find a relationship between repeated abortions of unknown etiology and caused of Mycoplasma hominis andor Ureplasma urealyticum.

Methods : one hundred sixty cases, (15-49 years old) with history of recurrent abortion, intrauterine fetal death andor neonatal death (after exclusion of other factors as cause abortion), and hundred women with normal pregnancy outcome with the same age were chosen as controls.

M.

homini and U.

urealyticum were detected in blood by PCR.

Result : M.

homini could be detected in 12160 (7.5 %) in women with pregnancy losses, but was not detected in control group.

U.

urealyticum could be detected in 64160 (40 %) in patient group and 4100 (4 %) in control group.

The rapid detection of M.

homini andor U.

urealyticum by PCR in pregnancy loss women could be important and necessary.

The detection rate of M.

homini andor U.

urealyticum in young women age (20-29 years) was higher than the others.

Significant difference was observed in patients with three or four abortions compare with 2 or one abortion in addition to history of adverse outcome.

Conclusion : the role M.

homini andor U.

urealyticum in the etiology of pregnancy losses was proposed.