Effect of topical cidir leaves extract in reducing skin sensitivity in atopic patients

Abstract EN

Objective : To determine the changes of Cutaneous sensations that occur after local application of cidir leaves extract in atopic patients and healthy individuals.

Methods : Thirty normal individuals and 30 patients with atopic dermatitis participated in the study.

The study was conducted in Najaf Teaching Hospital-Najaf in the period between October 2002 and March 2004.

The square wave electrical stimulator was used to stimulate fixed spots on the volar aspect of the right forearm before and after the application of cidir leaves extract.

The stimulus was increased gradually and the type of cutaneous sensation that occurred was reported.

Results : Cidir leaves extract decrease the skin sensitivity both in normal and effectively in atopic patients.

The mean stimulus required to induce each one of cutaneous sensation (tingling, pricking, itching and pain) was higher after the application of the cidir leaves extract.

The Cutaneous sensation on other hand that induced by the stimulus was milder than before application of the extract.

Conclusion : Cidir leaves extract decrease skin sensitivity both in atopic patients and healthy individuals so it can be used as a cooling agent in cases of eczema and pruritus.