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The role of white blood cells in acute coronary syndrome
Author
Source
Journal of the Faculty of Medicine Baghdad
Issue
Vol. 49, Issue 4 (31 Dec. 2007), pp.362-368, 7 p.
Publisher
University of Baghdad Faculty of Medicine
Publication Date
2007-12-31
Country of Publication
Iraq
No. of Pages
7
Main Subjects
Topics
Abstract EN
Background : Inflammation has been shown to play a role in atherosclerosis and acute coronary syndromes.
An elevated total WBC count has been associated with increased cardiovascular risk, but which leukocyte subtypes carry this risk.
is uncertain.
This study was designed to determine the effect of WBC count and other inflammatory markers on severity and outcome of patients with UA / NSTEMI.
Patients and Methods : Seventy (70) patients with UA / NSTEMI admitted to CCU at the Iraqi Center for Heart Diseases were subjected to thorough history and physical examination and WBC indices to find their relation to clinical severity and outcome for both in-hospital and / month after discharge.
The results were compared with other thirty (30) patients with chronic stable angina and thirty (30) healthy Fac Med Baghdad persons as two control groups.
Results : High total baseline total WBC was more prevalent in patient with UA / NSTEMI than in those with stable angina and normal persons (94.1 %, 5.9 %.
and 0 %) respectively.
High baseline neutrophil was found only in those with UA.
/ NSTEMI (100 %, 0 %, and 0 %).
High baseline Neutrophil / lymphocyte (N / L ratio) and Positive CRP were more prevalent in patients with UA/NSTEMI than in other two groups (92.3 %.
7.7 %.
0 %) and (98.5 %, 1 .5 %.
0 %) respectively.
Higher total baseline WBC count was significantly found in more severe Braunwald's class of those with UA / NSTEMI 6.3 %.
31.3 %.
and 50.5 % for patients with class I, II, III respectively.
The same was true for baseline high neutrophil count (6.7 %.
33.3 % to 60 %), high Baseline N / L ratio (7.7 %, 15 %.
and 21.6 %).
Patient in the UA / NSTEMI group with higher baseline WBC count had higher risk for death as compared to those of low and intermediate WBC count (0.00 %.
0.00 %.
and 100.00 %).
The same was true for those with higher baseline neutrophil count (0.00 %.
1.90 %, 20.00 %) and those with higher baseline N / L ratio (0.00 %.
25.000 %.
75.000 %) respectively.
Conclusions : Total baseline WBC and differential count is simple, cheap and widely available bedside test that predicted the severity of CAD and one month survival.
American Psychological Association (APA)
Shawki, Hilal B.. 2007. The role of white blood cells in acute coronary syndrome. Journal of the Faculty of Medicine Baghdad،Vol. 49, no. 4, pp.362-368.
https://search.emarefa.net/detail/BIM-338681
Modern Language Association (MLA)
Shawki, Hilal B.. The role of white blood cells in acute coronary syndrome. Journal of the Faculty of Medicine Baghdad Vol. 49, no. 4 (2007), pp.362-368.
https://search.emarefa.net/detail/BIM-338681
American Medical Association (AMA)
Shawki, Hilal B.. The role of white blood cells in acute coronary syndrome. Journal of the Faculty of Medicine Baghdad. 2007. Vol. 49, no. 4, pp.362-368.
https://search.emarefa.net/detail/BIM-338681
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 368
Record ID
BIM-338681