Synthesis and antibacterial evaluation of some pyrano-1, 3--oxazine derivatives
Joint Authors
Abd al-Ghani, A.
Bashir, H. A.
al-Ujayli, M. S.
Source
Issue
Vol. 26, Issue 2007 (30 Jun. 2007), pp.348-356, 9 p.
Publisher
University of Babylon College of Sciences
Publication Date
2007-06-30
Country of Publication
Iraq
No. of Pages
9
Main Subjects
Topics
Abstract AR
تم تحضير بعض مشتقات 1-3 بايرانو اوكسازين و هي تمثل الببتيدات الثنائية و بعض الأمينات و هي المركبات (2a-d) و (3a-e) على التوالي و تمت دراسة هذه المركبات ضد بعض أنواع البكتيريا (Bacelas Sabtilis, Staph Auroces) و قد كانت هناك فعالية ملحوظة لهذه المركبات ضد أنواع البكتيريا أعلاه، كما و قد درست هذه المركبات المحضرة بالطرق الطيفية IR و NMR.
Abstract EN
Some dipeptide amide and amino derivatives of 7-chloro-4,5-dioxopyrano [3,4-e]-l,3-oxazine, compounds (2a-d) and (3a-e) respectively have been synthesized and studied against five species of bacteria in vitro.
A significant activity against staph.
Aureus and Bacelus Subtilis were observed by the above derivatives at concentration ranging from (0.1-10 mg.
/ ml.) and remarkable activity was exhibited by 2-(N-glycyl glycine amido)-7-chloro-4,5-dioxopyrano [3,4-e]-l,3-oxazine (2a).
Other compounds showed no significant activities.
The I.R.
and NMR spectral data of the synthesized compounds were also discussed and are included.
American Psychological Association (APA)
al-Ujayli, M. S.& Bashir, H. A.& Abd al-Ghani, A.. 2007. Synthesis and antibacterial evaluation of some pyrano-1, 3--oxazine derivatives. National Journal of Chemistry،Vol. 26, no. 2007, pp.348-356.
https://search.emarefa.net/detail/BIM-338994
Modern Language Association (MLA)
al-Ujayli, M. S.…[et al.]. Synthesis and antibacterial evaluation of some pyrano-1, 3--oxazine derivatives. National Journal of Chemistry Vol. 26 (2007), pp.348-356.
https://search.emarefa.net/detail/BIM-338994
American Medical Association (AMA)
al-Ujayli, M. S.& Bashir, H. A.& Abd al-Ghani, A.. Synthesis and antibacterial evaluation of some pyrano-1, 3--oxazine derivatives. National Journal of Chemistry. 2007. Vol. 26, no. 2007, pp.348-356.
https://search.emarefa.net/detail/BIM-338994
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 355-356
Record ID
BIM-338994