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A randomized comparison of initial hemodynamic response between three concentrations of adrenaline in lignocaine with submucosal infiltration in septorhinoplasty patients
Joint Authors
al-Tamimi, Shawkat F.
al-Rawashidah, Muhammad
al-Khalidi, Hazim
Source
Journal of the Royal Medical Services
Issue
Vol. 20, Issue 3 (30 Sep. 2013), pp.37-43, 7 p.
Publisher
The Royal Medical Services Jordan Armed Forces
Publication Date
2013-09-30
Country of Publication
Jordan
No. of Pages
7
Main Subjects
Topics
Abstract EN
Objective : to assess the cardiovascular responses induced by different nasal adrenaline-lignocaine mixtures infiltrations protocols for patients undergoing septorhinoplasty under general anesthesia.
Methods : our prospective investigation enrolled 212 subjects, aged 26-34 yrs, classified as physical status class I by the American Society of Anesthesiologists (ASAI), of both sexes and scheduled for septorhinoplasty under general endotracheal anesthesia during the period from January 2010 to December 2012, at the King Hussein Hospital, King Hussein Medical Centre, Amman, Jordan.
Patients were divided randomly into three groups.
Patients in group A (n = 70) received nasal sub mucosal infiltration of 10.2 ml of lignocaine 1 % (10 mg / ml) with adrenaline 0.0025 % (25 mcg / ml).
Subjects in group B (n = 72) received 10.2 ml of lignocaine 1 % with adrenaline 0.00125% (12.5 mcg mg / ml), while subjects in group C (n = 70) received 10.2ml of lignocaine 1 % with adrenaline 0.000625 % (6.25 mcg / ml).
Cardiovascular parameters including heart rate, systolic blood pressure and mean arterial pressure were recorded every half minute during the first 5 minutes after nasal infiltration.
Inter-group statistical comparisons were performed using ANCOVA and intra-group statistical comparisons were achieved using ANOVA.
Results : in comparison with baseline readings, heart rate was mostly increased, systolic blood pressure was mostly decreased and mean arterial pressure was mostly reduced significantly (P < 0.05) at 60 seconds time interval post infiltration in all three groups.
Conclusions : local nasal sub mucosal infiltration of different adrenaline concentrations containing lignocaine solutions could increase heart rate and reduce mean arterial pressure during the first five minutes after infiltration.
American Psychological Association (APA)
al-Khalidi, Hazim& al-Tamimi, Shawkat F.& al-Rawashidah, Muhammad. 2013. A randomized comparison of initial hemodynamic response between three concentrations of adrenaline in lignocaine with submucosal infiltration in septorhinoplasty patients. Journal of the Royal Medical Services،Vol. 20, no. 3, pp.37-43.
https://search.emarefa.net/detail/BIM-339259
Modern Language Association (MLA)
al-Khalidi, Hazim…[et al.]. A randomized comparison of initial hemodynamic response between three concentrations of adrenaline in lignocaine with submucosal infiltration in septorhinoplasty patients. Journal of the Royal Medical Services Vol. 20, no. 3 (Sep. 2013), pp.37-43.
https://search.emarefa.net/detail/BIM-339259
American Medical Association (AMA)
al-Khalidi, Hazim& al-Tamimi, Shawkat F.& al-Rawashidah, Muhammad. A randomized comparison of initial hemodynamic response between three concentrations of adrenaline in lignocaine with submucosal infiltration in septorhinoplasty patients. Journal of the Royal Medical Services. 2013. Vol. 20, no. 3, pp.37-43.
https://search.emarefa.net/detail/BIM-339259
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 42-43
Record ID
BIM-339259