Lapin Escherichiae coli K1 vaginosis

Abstract EN

We used two groups of female rabbits.

First group was used to study the pathogenesis of Escherichiae colli serotype K1,second group was used to study the some immunological parameters.

Second group was divided into three sub groups, first was intravaginal inoculation with live bacteria (0,5*104), second was intravaginal inoculation with capsular antigen and third group was used as control.

After suitable period blood and autiopsies were collected from all subgroups to study humoral immunity (titration, immunoglobulin isotype, total protein concentration) and cellular immunity (Leukocytte inhibition factor,Macrophage migration inhibition factor, skin test).

Specific antibody titer was showed with capsuller antigen and cell free culture antigen and specific leucocyte inhibtion factor and macrophage migration inhibition factor were showed in test group and not seen in control group.

We concluded from this study that vaginal of rabbit female is part of common mucosal immune system because specific titer and cellular immunity were seen in intestinal parts.