Brucellosis as trigger for autoimmune hepatitis in susceptible individual
Author
Source
Journal of the Faculty of Medicine Baghdad
Issue
Vol. 49, Issue 4 (31 Dec. 2007), pp.467-469, 3 p.
Publisher
University of Baghdad Faculty of Medicine
Publication Date
2007-12-31
Country of Publication
Iraq
No. of Pages
3
Main Subjects
Topics
Abstract EN
Background : Autoimmune hepatitis (AIH) is a rare chronic liver disease of unknown etiology, characterized by hypergammaglobulinemia, characteristic autoantibodies, and a favorable response to immunosuppressive treatment.
Strong circumstantial evidences denoted that there is quite long list of environmental factors such as (food additives and drugs), viruses and toxins which play an important role in precipitating this disease.
Brucellosis is endemic in Iraq.
It may involve any organ in the body.
Liver is frequently involved.
Doxycycline used for treatment occasionally may lead to hepatotoxicity.
Objective : the aim of the study is To show the relationship between brucellosis, AIH, and hepatotoxicity of doxycycline.
Methods : the study was performed on 2 Iraqi patients with brucellosis, attending the teaching hospital for gastroenterology and liver disease in the period between November 2003 and July 2004.
Brucella were studied by Rose Bengal test and confirmed by indirect immuno florescence assay (IIF).
Results : anti-SLA / LP Abs was detected in 2 patients with brucellosis.
Conclusion : brucellosis or doxycycline is a trigger of AIH.
American Psychological Association (APA)
al-Ubaydi, Iman Sh.. 2007. Brucellosis as trigger for autoimmune hepatitis in susceptible individual. Journal of the Faculty of Medicine Baghdad،Vol. 49, no. 4, pp.467-469.
https://search.emarefa.net/detail/BIM-339518
Modern Language Association (MLA)
al-Ubaydi, Iman Sh.. Brucellosis as trigger for autoimmune hepatitis in susceptible individual. Journal of the Faculty of Medicine Baghdad Vol. 49, no. 4 (2007), pp.467-469.
https://search.emarefa.net/detail/BIM-339518
American Medical Association (AMA)
al-Ubaydi, Iman Sh.. Brucellosis as trigger for autoimmune hepatitis in susceptible individual. Journal of the Faculty of Medicine Baghdad. 2007. Vol. 49, no. 4, pp.467-469.
https://search.emarefa.net/detail/BIM-339518
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 468-469
Record ID
BIM-339518