Investigation of circulating anti-coxsackie B, anti-polio and anti-adeno IgG in newly diagnosed T1DM children
Joint Authors
Abd al-Muhaymin, Nidal
Salih, Iman M.
Source
Journal of the Faculty of Medicine Baghdad
Issue
Vol. 49, Issue 4 (31 Dec. 2007), pp.477-481, 5 p.
Publisher
University of Baghdad Faculty of Medicine
Publication Date
2007-12-31
Country of Publication
Iraq
No. of Pages
5
Main Subjects
Topics
Abstract EN
Background : Viruses may be involved in the pathogenesis of Type 1 Diabetes Mellitus (T1DM), either through direct β-cell infection or as triggers of autoimmunity.
Objective : To investigate the presence of specific anti-viral IgG antibodies for Coxsackie virus type B (CVB5), Poliovirus, and Adenovirus which proposed to be involved in the etiology of T1DM.
Subjects & methods : A total of 60 Iraqi T1DM children were included in the presents study.
They were new onset of the disease (diagnosis was from one week up to five months).
For the purpose of comparisons, 50 apparently healthy control subjects were selected.
Serum IgG against Coxsackie virus type B5, Adenovirus type 3, 4, and 7, and Poliovaccin Trivalent were detected quantitatively with an indirect ELISA.
Results : High proportion of anti-CVB5 IgG (20 %) (p < 0.05) and anti-Polio IgG (31.67 %) were found in T1DM children compared to controls (8 %, 26 % respectively), while anti-Adeno IgG were detected in diabetic patients only (6.67 %) (p < 1.0001).
American Psychological Association (APA)
Salih, Iman M.& Abd al-Muhaymin, Nidal. 2007. Investigation of circulating anti-coxsackie B, anti-polio and anti-adeno IgG in newly diagnosed T1DM children. Journal of the Faculty of Medicine Baghdad،Vol. 49, no. 4, pp.477-481.
https://search.emarefa.net/detail/BIM-339524
Modern Language Association (MLA)
Salih, Iman M.& Abd al-Muhaymin, Nidal. Investigation of circulating anti-coxsackie B, anti-polio and anti-adeno IgG in newly diagnosed T1DM children. Journal of the Faculty of Medicine Baghdad Vol. 49, no. 4 (2007), pp.477-481.
https://search.emarefa.net/detail/BIM-339524
American Medical Association (AMA)
Salih, Iman M.& Abd al-Muhaymin, Nidal. Investigation of circulating anti-coxsackie B, anti-polio and anti-adeno IgG in newly diagnosed T1DM children. Journal of the Faculty of Medicine Baghdad. 2007. Vol. 49, no. 4, pp.477-481.
https://search.emarefa.net/detail/BIM-339524
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 481
Record ID
BIM-339524