Effect of lidocaine, diclofenac and their mixture on some blood parameters in experimental mice

Abstract EN

The study included the evaluation of tire haematological effects resulting from intramuscular injection of (1 mg / kg) of Li! ocaine (group A) , Diclofenac (group B) and Lidocaine- Diclofenac mixture (group in experimental mice , as a result there was a significant decrease in haemoglobin dpncentration and reached it's lowest value in group C (7.

04 gm / 100ml ).

There was also a significant increase in both total WBCS cpunt and eosinophils number reached it's highest number in group C (9.

88 X 103 / mm’ , ll.

2 %) respectively, while the highest number basophils appeared in group B and reached ( 8 %) , the same group showed a significant decrease in neutrophils number which reached to (17.

6 %) .

the a granulocytes ( lymphocytes and monocytes ) showed no changes in number in all groups .