The effect of nandrolone decanoate on the epididymis weight and it's histological structure in adult male mice

Abstract EN

This study aimed to identify the effect of different doses of nandrolone decanoate on epididymis weight and histological changes in epididymis in adult male mice.

these males was injected subcutaneously (in distled region of femur) with (50, 100mg / kgm body weight) every 2 days for 30 days.

Histological section examination shows reduction of the diameter of epididymal tubules, the diameter of lumen of epididymal and the height of epithelial cells in (caput & cauda) of epididymis and increase the percentage of damage in epididymal caput tubules for treatment group in comparing with control group which injected with normal saline and realved histopathological changes includes accumulation of the odematous fluid inside the tubules, interstitial spaces between tubules, degreagation of epithelial epididymis and absence of tubules from sperm.