Biochemical bone indices and serum uric acid changes in postmenopausal women

Abstract EN

The objective of this study was to evaluate the effect of menopause on : body mass index (BMI), serum levels of total protein, albumin, globulin, total calcium, uric acid, activity of acid phosphatase (ACP) and tartarate-resistant acid phosphatase (TRACP 5b).

The study involves 50 participants who were categorized into two groups ; premenopausal women group (n = 25) (age, 47.18 ± 4.10 years) and postmenopausal women group (n = 25) (age, 58.58 ± 4.51years).

In comparative evaluation, the serum total protein, calcium, uric acid, activity of ACP and TRACP 5b were found to be significantly increased (p < 0.05) in post-menopausal women as compared to premenopausal women.

Postmenopausal women are exposed to a greater risk of serum biochemical changes as compared to the premenopausal women, thus leading to an increased risk of osteoporosis cardiovascular diseases after menopause.