Studies the effects of finastrides and diane or metformin, diane and andocur for treating subfertile women with poly cystic ovary syndrome

Abstract EN

Sub fertility is the inability of a couple to conceive after one year of unprotected coitus in women less than 35 years and six months in women over35 years .It carries significant personal, social and financial consequences, one half of sub fertility causes due to female causes and one third of the female causes is the an-ovulation and the commonest cause of an-ovulation is the poly cystic ovary Syndrome.

Objective : the aim of this study to evaluate the benefits of Fin strides and Diane versus Metformin, Diane and Adour on fertility in poly cystic ovary Syndrome with moderate to severe hyperandrogenism.

Patients and Methods : During a period between first of March 2010 and first of September 2010 a prospective study was performed on 90 patients from infertility centre and outpatient clinic in Babylon Maternity and Paediatrics Teaching Hospital.

We divided them into three groups: Group A, 30 women received Fin stride and Diane, Group B,30 women received Metformin, Diane andAndocur while Group C, 30 were normal as a control.

Results : It showed that the commonest age group affected with poly cystic ovary Syndrome were (25-35) years with history of primary infertility and larger body mass index.

There is greater reduction in the LH level in both treatment regimens while in prolactin there’s little increment after treatment in Group B, it may be due to cyproterone acetate.

Conclusion: Our study showed significant response in both treatment groups A and B support the effect that in poly cystic ovary Syndrome with sub fertility and hyperandrogenism we can use Finstride with Diane or Metformin, Diane and Andocur to restore fertility.