Mean platelet volume, platelet distribution width and plateletcrit values in differentiating clonal from secondary thrombocytosis

Abstract EN

Objective : to assess whether platelet indices [platelet count, mean platelet volume (MPV), platelet distribution width (PDW)) and plateletcrit (PCT) could serve as diagnostic tools to differentiate between primary and secondary thrombocytosis.

Subjects and Methods : A total of 83 Iraqi patients with thrombocytosis attending the Iraqi centre for cancer research & medical genetics and the National Iraqi Centre for Blood Diseases were included in this prospective case series study.

A group of 20 healthy persons were included as a control.

Complete blood count was done using Mindwayhaematologicautoanalyser.

Results: Mean platelet volume, platelet distribution width & plateletcrit in primary thrombocytosis were significantly higher than in secondary thrombocytosis.

In primary thrombocytosis group platelet count inversely correlate with both Hb & MCV, while in secondary thrombocytosis platelet count inversely correlates with MCV only but less significantly than the correlation found in primary thrombocytosis.