Detection of latent autoimmune diabetes of adults among type 2 diabetic patients using glutamic acid decarboxylase antibodies

Abstract EN

Background : latent autoimmune diabetes of adults (LADA) is a slowly progressive form of autoimmune diabetes initially managed with diet and oral hypoglycemic agents before becoming insulin requiring.

GADA are used for differential diagnosis between LADA and type 2 diabetes.

Objectives : to assess the prevalence of LADA among type 2 diabetic patients using glutamic acid decarboxylase (GAD) antibodies.

Methods: Cross sectional study conducted on 100 patients with primary diagnosis of T2DM, 52 female and 48 male, aged 30-70 years.

The GADA test is used for diagnosis of LADA patients.

Results : out of 100 patients with primary diagnosis of T2DM, 14 patients (14 %) were positive for GADA.

Conclusions : LADA patients accounts for 14 % of T2DM using GADA assay.

Age, sex, and BMI had no significant effect on the prevalence of LADA patients among T2DM.