Changes in testosterone, progesterone and prolactin levels in pregnant women with chronic toxoplasmosis

Abstract EN

The present investigation dealt with studying the influence of chronic infection by protazoan parasite Toxoplasma gondii on levels testosterone, progesterone and prolactin hormones in pregnant women through trimesters of pregnancy.

A total number of 55 pregnant women with chronic toxoplasmosis(Seropositive IgG) and 51 healthy pregnant (Seronegative IgG) were used.

The results revealed that chronic infection by T.

gondii exhibited significant increase of testosterone serum levels and significant decreased of prolactin serum levels in all trimesters.

we found no significant difference in progesterone levels in overall seropositive IgG pregnant women, We have detected fluctuation in levels of progesterone from trimesters to other, in first trimester progesterone levels did not show significant variation, significant decrease in progesterone levels in seropositve IgG in second trimester while a significant increase occurred to progesterone in seropositive IgG pregnant women when compared with those of the control group during third trimester.

Testosterone, progesterone and prolactin concentrations were highest in the 3rd trimester.

We can conclude that chronic infection by T.

gondii in pregnant women associated with variations in levels of testosterone, progesterone and prolactin hormones and these variations may be influences the probability of the Toxoplasma infection or that infection changes the concentration of hormones in infected host as adaptive stratagem enhance parasite survival in host.