In vitro study of mefenamatestarch as drug delivery system
Other Title(s)
دراسة حيوية لبوليمر المفبناميت-النشا كنظام دوائي جديد
Joint Authors
Ali, Huda Muhammad
Rahi, Firas Aziz
Ali, Firyal Muhammad
Hasan, Asil Qasim Muhammad
Source
Issue
Vol. 10, Issue 3 (30 Sep. 2013), pp.954-964, 11 p.
Publisher
University of Baghdad College of Science for Women
Publication Date
2013-09-30
Country of Publication
Iraq
No. of Pages
11
Main Subjects
Topics
Abstract AR
تم أسترة حامض المفينامك مع النشا بنسبة مولية [1 : 1] كتعويض دواء على بوليمر طبيعي لغرض إطالة فترة التحرر الدوائي و لفوائد أخرى.
شخص البوليمر الدوائي الجديد بواسطة طيف الأشعة تحت الحمراء و الأشعة فوق البنفسجية و طيف الرنين النووي المغناطيسي.
قيست الصفات الفيزيائية و درست سرع التحرر الدوائي المحكم بدوال حامضية 1.1 و 7.4 للمعدة و الأمعاء و بدرجة 37°م.
Abstract EN
Mefenamic acid was esterified with starchwith [1 : 1] Molar ratio, as drug substituted with natural polymer, to prolongthe period of hydrolysis of drug polymer with other advantages.
The new prodrug starch was characterized by FT-IR and UV-Visible and 1H-NMR spectroscopies.
The physical properties were studied and controlled drug release was studied in different pH values at 37oC.
The stability of drug was carried out by measuring the absorbance of mefenamic starch which hydrolyzed in HCl solution of pH 1.1 (artificial gastric fluid) and phosphate buffer of pH 7.4 (simulating intestinal fluid SIF) at 37oC for several days.
The thermal analysis such as DSC was studied.
American Psychological Association (APA)
Ali, Firyal Muhammad& Rahi, Firas Aziz& Hasan, Asil Qasim Muhammad& Ali, Huda Muhammad. 2013. In vitro study of mefenamatestarch as drug delivery system. Baghdad Science Journal،Vol. 10, no. 3, pp.954-964.
https://search.emarefa.net/detail/BIM-343263
Modern Language Association (MLA)
Ali, Firyal Muhammad…[et al.]. In vitro study of mefenamatestarch as drug delivery system. Baghdad Science Journal Vol. 10, no. 3 (2013), pp.954-964.
https://search.emarefa.net/detail/BIM-343263
American Medical Association (AMA)
Ali, Firyal Muhammad& Rahi, Firas Aziz& Hasan, Asil Qasim Muhammad& Ali, Huda Muhammad. In vitro study of mefenamatestarch as drug delivery system. Baghdad Science Journal. 2013. Vol. 10, no. 3, pp.954-964.
https://search.emarefa.net/detail/BIM-343263
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 963
Record ID
BIM-343263
