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Comparative studies on anti-hyperglycemic effects of ethyl acetate and methanol extract of Albizzia lucida benth bark in alloxan induced diabetic rats
Joint Authors
Kumar, Arumugam S.
Kavimani, Subramanian
Jayaveera, Korlakunta N.
Source
Jordan Journal of Biological Sciences
Issue
Vol. 6, Issue 4 (31 Dec. 2013), pp.300-307, 8 p.
Publisher
The Hashemite University Deanship of Academic Research and Graduate
Publication Date
2013-12-31
Country of Publication
Jordan
No. of Pages
8
Main Subjects
Topics
Abstract EN
The decoction of the bark of Albizzia lucida Benth was used in ayurvedic system for management of diabetes mellitus.
To confirm the traditional claim, the comparative anti-hyperglycemic efficiency of ethyl acetate extract of bark of Albizzia lucida Benth.
(EEAL) and methanol extract of bark of Albizzia lucida Benth.
(MEAL) was done in alloxan induced diabetic rats.
Acute and sub-acute effect of oral administration of EEAL and MEAL (200 & 400 mg / kg, b.wt) on blood glucose was observed in different time interval for 10 days.
By the end of the study, the collected blood sample and pancreas was used for estimation of serum lipid profile and histological studies.
EEAL and MEAL showed that the serum blood glucose and serum lipids (total cholesterol, triglyceride, VLDL-cholesterol, LDL-cholesterol) was reduced significantly (p < 0.01) in dose dependent manner when compare to control group.
At the same time MEAL was showed potent effect than EEAL.
EEAL and MEAL does not affect the body weight and alter the histopathology of pancreas similar to that of normal.
It was concluded that EEAL extract of bark of Albizzia lucida Benth and MEAL extract of bark of Albizzia lucida Benth.
Possess anti-hyperglycemic activity in alloxan-induced diabetic model rats.
American Psychological Association (APA)
Kumar, Arumugam S.& Kavimani, Subramanian& Jayaveera, Korlakunta N.. 2013. Comparative studies on anti-hyperglycemic effects of ethyl acetate and methanol extract of Albizzia lucida benth bark in alloxan induced diabetic rats. Jordan Journal of Biological Sciences،Vol. 6, no. 4, pp.300-307.
https://search.emarefa.net/detail/BIM-344642
Modern Language Association (MLA)
Kumar, Arumugam S.…[et al.]. Comparative studies on anti-hyperglycemic effects of ethyl acetate and methanol extract of Albizzia lucida benth bark in alloxan induced diabetic rats. Jordan Journal of Biological Sciences Vol. 6, no. 4 (Dec. 2013), pp.300-307.
https://search.emarefa.net/detail/BIM-344642
American Medical Association (AMA)
Kumar, Arumugam S.& Kavimani, Subramanian& Jayaveera, Korlakunta N.. Comparative studies on anti-hyperglycemic effects of ethyl acetate and methanol extract of Albizzia lucida benth bark in alloxan induced diabetic rats. Jordan Journal of Biological Sciences. 2013. Vol. 6, no. 4, pp.300-307.
https://search.emarefa.net/detail/BIM-344642
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 307
Record ID
BIM-344642