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Amylin level and gastric emptying in obese children : before and after weight loss
Joint Authors
al-Rashidi, Umniyah F.
Amin, Dina A.
al-Maisri, Hisham
Ahmad, Halah A.
Muntasir, Zaynab M.
Source
Journal of the Egyptian Society of Parasitology
Issue
Vol. 42, Issue 2 (31 Aug. 2012), pp.431-442, 12 p.
Publisher
The Egyptian Society of Parasitology
Publication Date
2012-08-31
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Topics
Abstract EN
Amylin is a neuroendocrine hormone that inhibits food intake and gastric emptying in animal studies.
Its role in obese human beings is still controversial.
We aimed to estimate the fasting and postprandial amylin levels in obese children before and after weight loss [through weight loss intervention program (WLIP)] and to relate these levels to the lipid profile, homeostasis model assessment of insulin resistance (HOMA-IR) and ultrasonography gastric half emptying time (t1 / 2).
This study was conducted initially on 20 obese children, 10 of them only continued 6 months follow up strategy on WLIP.
Ten lean children served as controls.
All children were subjected initially and on follow up to dietetic history taking, anthropometric measurements and laboratory assessment of lipid profile, HOMA-IR, fasting and postprandial amylin levels and ultrasonography gastric half emptying time (t1 / 2).
The results showed that IR, significantly increased in fasting and postprandial amylin levels and significant delay in gastric emptying among obese children.
After WLIP completion, IR was reversible, fasting and postprandial amylin levels decreased and gastric emptying significantly improved yet still significantly delayed than controls.
There was significant positive correlation between fasting amylin levels and body mass index %, fasting insulin and HOMA-IR.
American Psychological Association (APA)
al-Rashidi, Umniyah F.& Amin, Dina A.& Ahmad, Halah A.& al-Maisri, Hisham& Muntasir, Zaynab M.. 2012. Amylin level and gastric emptying in obese children : before and after weight loss. Journal of the Egyptian Society of Parasitology،Vol. 42, no. 2, pp.431-442.
https://search.emarefa.net/detail/BIM-347471
Modern Language Association (MLA)
al-Rashidi, Umniyah F.…[et al.]. Amylin level and gastric emptying in obese children : before and after weight loss. Journal of the Egyptian Society of Parasitology Vol. 42, no. 2 (Aug. 2012), pp.431-442.
https://search.emarefa.net/detail/BIM-347471
American Medical Association (AMA)
al-Rashidi, Umniyah F.& Amin, Dina A.& Ahmad, Halah A.& al-Maisri, Hisham& Muntasir, Zaynab M.. Amylin level and gastric emptying in obese children : before and after weight loss. Journal of the Egyptian Society of Parasitology. 2012. Vol. 42, no. 2, pp.431-442.
https://search.emarefa.net/detail/BIM-347471
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 440-442
Record ID
BIM-347471