The contraction effect of Allium Porrum seeds on isolated intestine of rabbits

Abstract EN

Greater attention has been paid to the traditional medical practices in general and herbal medicine in particular even in the developed countries.

This study aimed to investigate Allium porrum seeds for its potential contraction or relaxation effect on small intestine in rabbits by using organ bath in vitro.

In order to establish a dose-response curve for the plant, six male rabbits were used in the experiment.

Pharmacological studies of the plant were done by comparing between intestinal contraction after addition of the plant alone as agonist, and intestinal contraction after the addition ofboth antaigon”ist’iidrugs then the plant extract.

A Allium porrum, showed a statistically significant dose-depend increase of intestinal contraction.Atropine, adrenaline, and chlorpheniramine reduce the effect of A.

porrum on intestinal contraction.

Both cholinergic and adrenergic mechanisms may involve the action of the plant with more potent muscarinic action