Anti-nociceptive effect of Nigella Sativa oil, apple vinegar, honey and their combinations in laboratory mouse

Other Title(s)

التأثير المضاد للألم لزيت الحبة السوداء و خل التفاح و العسل و مزجهم في الفئران المختبرية

Joint Authors

Jawad, Ala al-Din Hasan
Jasim, Nawfal Hammadi
Jasim, Abd Allah Muhammad

Source

Basrah Journal of Veterinary Research

Issue

Vol. 5, Issue 2 (31 Dec. 2006), pp.183-188, 6 p.

Publisher

University of Basrah College of Veterinary Medicine

Publication Date

2006-12-31

Country of Publication

Iraq

No. of Pages

6

Main Subjects

Biology

Topics

Abstract AR

أجريت محاولة دراسة التأثير المسكن لزيت الحبة السوداء و خل التفاح و العسل و مزجهم.

هذه المواد أعطيت عن طريق الفم إلى ذكور الفئران و فحصت باستخدام النموذج الحيواني للألم (فحص الصفيحة الحارة).

أظهرت النتائج بأن لزيت الحبة السوداء تأثير مسكن جيد و ذلك بزيادة فترة الصفيحة الحارة بنسبة 57.7 %.

و نفس التأثير وجد بواسطة خل التفاح.

أما العسل فكان أقل تأثيرا فقد سبب زيادة بنسبة 52 % في فترة الصفيحة الحارة.

و قد لوحظ بأن تأثير خل التفاح و العسل كان معتمدا على الجرعة.

أما مزج الحبة السوداء مع الخل أو العسل فلم يحسن تأثير الحبة السوداء، مع هذا فقد وجد تأثير مقوي بين الحبة السوداء و خل التفاح عند قياس التأثير المسكن بعد 4 و 6 ساعة من الزرق الفموي.

Abstract EN

An attempt wasmade to study the analgesic effect of oil extract of Nigella sativa .

seed, apple vinegar, honey and their combination.

These materials were administered orally to male mice and were tested using a model of animal of pain (hot plate test).

The result showed that N.

sativa oil had a good analgesic effect, increasing hot plate latencies by 57.7%.

Similar analgesic effect was produced by apple vinegar.

Honey was much less effective; it produced only 52% increase in hot plate time.

The effect of apple vinegar and honey was dose dependent.

Combination of N.

sativa with vinegar or honey did not result in enhancement of effect of N.

saliva oil when measured, one hour after administration.

However, potentiation effect was found between N.

sativa oil and apple vinegar when the analgesic effect was measured at 4 and 6 hours after oral administration.

American Psychological Association (APA)

Jawad, Ala al-Din Hasan& Jasim, Nawfal Hammadi& Jasim, Abd Allah Muhammad. 2006. Anti-nociceptive effect of Nigella Sativa oil, apple vinegar, honey and their combinations in laboratory mouse. Basrah Journal of Veterinary Research،Vol. 5, no. 2, pp.183-188.
https://search.emarefa.net/detail/BIM-348629

Modern Language Association (MLA)

Jawad, Ala al-Din Hasan…[et al.]. Anti-nociceptive effect of Nigella Sativa oil, apple vinegar, honey and their combinations in laboratory mouse. Basrah Journal of Veterinary Research Vol. 5, no. 2 (2006), pp.183-188.
https://search.emarefa.net/detail/BIM-348629

American Medical Association (AMA)

Jawad, Ala al-Din Hasan& Jasim, Nawfal Hammadi& Jasim, Abd Allah Muhammad. Anti-nociceptive effect of Nigella Sativa oil, apple vinegar, honey and their combinations in laboratory mouse. Basrah Journal of Veterinary Research. 2006. Vol. 5, no. 2, pp.183-188.
https://search.emarefa.net/detail/BIM-348629

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references : p. 188

Record ID

BIM-348629