Synthesis and characterization of oxazepine and oxazepane from reaction of (5,5-Diethyl-4, 6-dioxo-tetrahydro-pyrimidin-2-ylidein) -urea and 1, 3-Bis(5,5-diethyl-4, 6-dioxo-tetrahydro-pyrimidin-2-ylidein) - urea with maleic and succinic anhydride
Joint Authors
al-Hadithi, Muhammad A.
al-Hiti, Walid F.
Source
Issue
Vol. 2006, Issue 23 (30 Sep. 2006), pp.405-417, 13 p.
Publisher
University of Babylon College of Sciences
Publication Date
2006-09-30
Country of Publication
Iraq
No. of Pages
13
Main Subjects
Abstract AR
تم تحضير قواعد شيف (5,5 ثنائي اثيل-4,6-دايوكسو-رباعي هيدرو-بيرميدين-2-يل أدين ثايويوريا)-يوريا 3,1- بس (5,5- ثنائي اثيل -4,6- دايوكسو – رباعي هيدرو- بيرامادين -2- يل أدين)- يوريا من تكثيف اليوريا مع مول واحد و مولين من 5,5- ثنائي اثيل-بيرميدين- 2,4,6- ترايون.
فوعلت قواعد شيف هذه مع مول واحد من انهيدريدات كل من الماليك و السكسنيك وتم الحصول على نظام حلقي غير متجانس (سباعي الحلقة) و عند مفاعلة قواعد شيف مع مولين من الانهيدريدات أنفة الذكر أعطى نظام حلقي غير متجانس (بحلقتين سباعيتين).
و قد شخصت المركبات المحضرة بتعيين درجات انصهارها, تحليل العناصر, أطياف الأشعة فوق البنفسجية , أطياف الأشعة تحت الحمراء و أطياف الرنين النووي المغناطيسي لبعض منها.
و قد أسهمت نتائج التشخيص بالطرق المختلفة في إثبات الصيغ التركيبية للمركبات المحضرة.
Abstract EN
(5,5-Diethyl-4,6-dioxo-tetrahydro-pyrimidin-2-ylidein)-urea and 1,3-Bis(5,5- diethyl-4,6-dioxo-tetrahydro-pyrimidin-2-ylidein)- urea were prepared by condensation of urea with one equivalent and two equivalent of 5,5-Diethyl-pyrimidine-2,4,6-trione.
These Schiff-bases reacted with one equivalent of maleic and succinic anhydride in absolute ethanol to give 7-membered heterocyclic ring system of 3,3-Diethyl-2,4,8- tetraoxo-7-oxa-1,5,12-triaza-spiro [5.6] dodec-9-ene-12-carboxylic acid amide and were reacted with two equivalent of maleic and succinic anhydride in same solvent give doubled (7-membered) heterocyclic ring system of 12-(3,3-Diethyl-2,4,8,11-tetraoxo-7- oxa-1,5,12-triaza-spiro[5.6]dodecane-12-carbonoyl)-3-ethyl-3-methyl-7-oxa-1,5,12- triaza-spiro[5.6]dodec-9-ene-2,4,8,11-tetraone.
The final products were identified by there m.ps, elemental analyses,IR, 1HNMR and UV-Visible spectra.
American Psychological Association (APA)
al-Hiti, Walid F.& al-Hadithi, Muhammad A.. 2006. Synthesis and characterization of oxazepine and oxazepane from reaction of (5,5-Diethyl-4, 6-dioxo-tetrahydro-pyrimidin-2-ylidein) -urea and 1, 3-Bis(5,5-diethyl-4, 6-dioxo-tetrahydro-pyrimidin-2-ylidein) - urea with maleic and succinic anhydride. National Journal of Chemistry،Vol. 2006, no. 23, pp.405-417.
https://search.emarefa.net/detail/BIM-348918
Modern Language Association (MLA)
al-Hiti, Walid F.& al-Hadithi, Muhammad A.. Synthesis and characterization of oxazepine and oxazepane from reaction of (5,5-Diethyl-4, 6-dioxo-tetrahydro-pyrimidin-2-ylidein) -urea and 1, 3-Bis(5,5-diethyl-4, 6-dioxo-tetrahydro-pyrimidin-2-ylidein) - urea with maleic and succinic anhydride. National Journal of Chemistry No. 23 (2006), pp.405-417.
https://search.emarefa.net/detail/BIM-348918
American Medical Association (AMA)
al-Hiti, Walid F.& al-Hadithi, Muhammad A.. Synthesis and characterization of oxazepine and oxazepane from reaction of (5,5-Diethyl-4, 6-dioxo-tetrahydro-pyrimidin-2-ylidein) -urea and 1, 3-Bis(5,5-diethyl-4, 6-dioxo-tetrahydro-pyrimidin-2-ylidein) - urea with maleic and succinic anhydride. National Journal of Chemistry. 2006. Vol. 2006, no. 23, pp.405-417.
https://search.emarefa.net/detail/BIM-348918
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 416-417
Record ID
BIM-348918