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A comparison of the effects of valsartan and captopril monotherapy on hepatic enzymes activities
Author
Source
Annals of the College of Medicine Mosul
Issue
Vol. 32, Issue 1-2 (31 Dec. 2006), pp.63-66, 4 p.
Publisher
University of Mosul College of Medicine-Mosul
Publication Date
2006-12-31
Country of Publication
Iraq
No. of Pages
4
Main Subjects
Abstract EN
Objective: This study was conducted to assess the effect of valsartan and captopril, each as monotherapy in hypertensive patients, on hepatic enzymes activities including alanine aminotransferase (ALT), aspartate aminotransferase (AST) and alkaline phosphatase (ALP).Patients and methods: Thirty nine hypertensive patients were included in the study, 20 of them using captopril and 19 using valsartan.
Serum ALT, AST, and ALP activities were measured before and after 2 months of starting treatment.Results: Patients on captopril showed significantly increased mean level of ALT and AST (P<0.001),( although still within normal limits) while mean ALP levels showed no significant difference.
In the valsartan group, mean ALT, AST and ALP values showed insignificant differences.Conclusion: In hypertensive patients with liver disease, valsartan may be more suitable than captopril for the potential influence of the latter on serum transaminase levels..
American Psychological Association (APA)
Ahmad, Ashraf H.. 2006. A comparison of the effects of valsartan and captopril monotherapy on hepatic enzymes activities. Annals of the College of Medicine Mosul،Vol. 32, no. 1-2, pp.63-66.
https://search.emarefa.net/detail/BIM-350873
Modern Language Association (MLA)
Ahmad, Ashraf H.. A comparison of the effects of valsartan and captopril monotherapy on hepatic enzymes activities. Annals of the College of Medicine Mosul Vol. 32, no. 1-2 (2006), pp.63-66.
https://search.emarefa.net/detail/BIM-350873
American Medical Association (AMA)
Ahmad, Ashraf H.. A comparison of the effects of valsartan and captopril monotherapy on hepatic enzymes activities. Annals of the College of Medicine Mosul. 2006. Vol. 32, no. 1-2, pp.63-66.
https://search.emarefa.net/detail/BIM-350873
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 66
Record ID
BIM-350873