Preparation and characterization of 1, 3-dioplar cycloaddition of nitrones to N-phenyl maleimide

Abstract EN

It was found that the cycloaddition of α-(4-Methoxy)phenyl-N-Phenyl nitrone (1)to N-Phenyl maleimide gives the syn isoxazolidine (3),whereas α-(2- fluoro) phenyl-N-phenyl nitrone (2)to the same compound gives the antiisoxazolidine (4), which has been identified by the IR spectroscopy, CHN analysis, Mass spectrometry and H-NMR spectra from two isoxazolidines compounds.