Photosynthesis of dimeric cinnamaldehyde, eugenol, and safrole as antimicrobial agents

Abstract EN

It has been reported that trans-cinnamaldehyde, eugenol and safrole inhibited bacteria and fungi growth in vivo mode.

In order to improve their biological activity, dimeric cinnamaldehyde, eugenol and safrole have been photosynthesized.

The photosynthesis compounds were 4-6 diphenyl-1, 2-dioxane-3, 5-dicarboxaldehyde, 4, 4-(cyclobutone-1, 3-diyl bis (methylene)) bis (2-methoxyphenal), and 3,6-bis (benzo[d] [1, 3] dioxol-5-ylmethyl)-1, 2-dioxane.

These new dimeric compounds strongly inhibited Candida albicans growth more than the monomers.