Lipid peroxidation and some haematological changes in Entamoeba histolytica patients

Abstract EN

Hospital based study was conducted on 57 patients of AL-Zahrawy hospital returners in Mosul city, to investigate the role of intestinal protozoan patients Entamoeba histolytica infection in lipid peroxidation and some haematological parameters in human.

The results revealed that plasma malondialdehyde (MDA) level (µmole/l.) was significanty higher in patients both females and males (5.322 ± 0.478,4.157 ±0.495) respectively, as compared with its level in healthy females (2.266 ±0.215) and male (2.037 ±0.288).

while the glutathione (GSH) level (µmole/l.)in plasma was significantly decreased in patients both in females and males(5.599 ±0.561,7.942 ±0.495) respectively, as compared with its level in healthy females (12.526 ±1.445) and males(14.363 ±1.321).

hemoglobin content (g/dl.) of patients was significantly decreased both in females and males (9.329 ±1.137 ,11.955 ±1.214) respectively, as compared with healthy females (10.664 ± 2.66) and males (15.096 ±1.836), also the packed cell volume was decreased in patients both females and males (27.926 ±2.73 , 30.233 ±2.88) respectively, as compared with healthy females (30.05±2.075) and males (46.55±3.179).

In conclusion, Entamoeba histolytica infection resulted in high plasma MDA level and low GSH level beside anemia.