Synthesis, characterization and in vitro antimicrobial activity of some novel 5-substituted schiff and mannich base of isatin derivatives
Joint Authors
Prakash, Chinnasamy Rajaram
Raja, Sundararajan
Source
Journal of Saudi Chemical Society
Issue
Vol. 17, Issue 3 (31 Jul. 2013), pp.337-344, 8 p.
Publisher
Publication Date
2013-07-31
Country of Publication
Saudi Arabia
No. of Pages
8
Main Subjects
Abstract EN
With the aim of developing potential antimicrobials, a series of novel Ciprofloxacin methylene isatin derivatives incorporating different aromatic aldehydes were synthesized and characterized by FTIR, 1H NMR, Mass spectroscopy and bases of elemental analysis.
In addition, the in vitro antibacterial and antifungal properties were tested against some human pathogenic microorganisms by employing the disc diffusion technique.
A majority of compounds were showing activity against several of the microorganisms.
The relationship between the functional group variation and the biological activity of the evaluated compounds is discussed.
From comparisons of the compounds 3c was determined to be the most active compound.
American Psychological Association (APA)
Prakash, Chinnasamy Rajaram& Raja, Sundararajan. 2013. Synthesis, characterization and in vitro antimicrobial activity of some novel 5-substituted schiff and mannich base of isatin derivatives. Journal of Saudi Chemical Society،Vol. 17, no. 3, pp.337-344.
https://search.emarefa.net/detail/BIM-351697
Modern Language Association (MLA)
Prakash, Chinnasamy Rajaram& Raja, Sundararajan. Synthesis, characterization and in vitro antimicrobial activity of some novel 5-substituted schiff and mannich base of isatin derivatives. Journal of Saudi Chemical Society Vol. 17, no. 3 (Jul. 2013), pp.337-344.
https://search.emarefa.net/detail/BIM-351697
American Medical Association (AMA)
Prakash, Chinnasamy Rajaram& Raja, Sundararajan. Synthesis, characterization and in vitro antimicrobial activity of some novel 5-substituted schiff and mannich base of isatin derivatives. Journal of Saudi Chemical Society. 2013. Vol. 17, no. 3, pp.337-344.
https://search.emarefa.net/detail/BIM-351697
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 344
Record ID
BIM-351697