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Thermal stability of anti-rheumatic pharmaceutical drugs parecoxib sodium and valdecoxib
Joint Authors
Sultan, Muhammad
al-Nahari, Talib T.
al-Rayyis, Mahmud A.
Mabkhut, Yahya Nasir
al-Husam, Abd Allah M.
Source
Journal of Saudi Chemical Society
Issue
Vol. 16, Issue 2 (30 Apr. 2012), pp.177-182, 6 p.
Publisher
Publication Date
2012-04-30
Country of Publication
Saudi Arabia
No. of Pages
6
Main Subjects
Abstract EN
Thermal analysis of antirheumatic drugs, parecoxib sodium (PCX) and valdecoxib (VCX) was achieved.
Thermogravimetry (TG), derivative thermogravimetry (DTG), and differential thermal analysis (DTA) were used through the work.
The results led to thermal stability data, and also to the determination of kinetic parameters such as activation energy and frequency factor.
The differential scanning calorimetry (DSC) was suitable for the purity determination of the compounds.
The simplicity, speed, and low operational costs of thermal analysis justify its application in the quality control of pharmaceutical drugs.
American Psychological Association (APA)
al-Nahari, Talib T.& al-Rayyis, Mahmud A.& Sultan, Muhammad& Mabkhut, Yahya Nasir& al-Husam, Abd Allah M.. 2012. Thermal stability of anti-rheumatic pharmaceutical drugs parecoxib sodium and valdecoxib. Journal of Saudi Chemical Society،Vol. 16, no. 2, pp.177-182.
https://search.emarefa.net/detail/BIM-351720
Modern Language Association (MLA)
al-Nahari, Talib T.…[et al.]. Thermal stability of anti-rheumatic pharmaceutical drugs parecoxib sodium and valdecoxib. Journal of Saudi Chemical Society Vol. 16, no. 2 (Apr. 2012), pp.177-182.
https://search.emarefa.net/detail/BIM-351720
American Medical Association (AMA)
al-Nahari, Talib T.& al-Rayyis, Mahmud A.& Sultan, Muhammad& Mabkhut, Yahya Nasir& al-Husam, Abd Allah M.. Thermal stability of anti-rheumatic pharmaceutical drugs parecoxib sodium and valdecoxib. Journal of Saudi Chemical Society. 2012. Vol. 16, no. 2, pp.177-182.
https://search.emarefa.net/detail/BIM-351720
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 182
Record ID
BIM-351720