Purification and characterization of Streptococcus pyogenes superantigen (Spe-C)
Other Title(s)
تنقية و توصيف المستضد الخارق نوع (Spe-C) المعزول من Streptococcus pyogenes
Joint Authors
al-Muzaffar, Sami A.
Isa, Rajwa Hasan
Salim, Hana
Salim, Ibtisam
Source
Issue
Vol. 8, Issue 4 (31 Dec. 2011), pp.956-961, 6 p.
Publisher
University of Baghdad College of Science for Women
Publication Date
2011-12-31
Country of Publication
Iraq
No. of Pages
6
Main Subjects
Topics
Abstract AR
تم جمع 144 عينة من مرضى التهاب اللوزتين بعمر (12 - 3) سنة.
كان 70 عزلة منها محللة لدم نوع بيتا و قد تم تشخيص 28 عزلة على أنها Streptococcus pyrogenes.
أجري اختبار الحساسية للمضادات الحيوية و قد وجد أن جميع العزلات حساسة للاموكسسلين و السيفالكسين بينما تمتلك مقاومة عالية للارثرومايسين.
تم اختيار عزلة واحدة و هي 100A ذات صفات ثابتة و تنتج السم الرافع للحرارة (pyrogenic toxin). تم تنقية السم الرافع للحرارة نوع C من الرائق الخالي من الخلايا و تم دراسة و تشخيص السم.
هذا السم و هو مستضد خارق له وزن جزيئي 24.000 دالتون و نقطة تعادل كهربائي 6.8 (PI) و هو يثبط بالحرارة و يهضم بالإنزيمات مثل الببسين و التربسين.
Abstract EN
From 144 specimens of tonsillitis which were collected from patient, (children of 3-12 year olds) there were 70 isolates beta hemolytic and 28 isolates were identified as S.
pyogenes.
Sensitivity of S.
pyogenes isolates to antibiotics was tested, all isolates were sensitive to amoxicillin and cephaloxia while higher resistant were to erythromycin.
One isolate whiche was 100 A had a stable characteristics and produce pyrogenic toxin was chosen for study and it was purified and characterized from the cell free supernatant of S.
pyrogenes strain.
American Psychological Association (APA)
al-Muzaffar, Sami A.& Isa, Rajwa Hasan& Salim, Hana& Salim, Ibtisam. 2011. Purification and characterization of Streptococcus pyogenes superantigen (Spe-C). Baghdad Science Journal،Vol. 8, no. 4, pp.956-961.
https://search.emarefa.net/detail/BIM-353669
Modern Language Association (MLA)
al-Muzaffar, Sami A.…[et al.]. Purification and characterization of Streptococcus pyogenes superantigen (Spe-C). Baghdad Science Journal Vol. 8, no. 4 (2011), pp.956-961.
https://search.emarefa.net/detail/BIM-353669
American Medical Association (AMA)
al-Muzaffar, Sami A.& Isa, Rajwa Hasan& Salim, Hana& Salim, Ibtisam. Purification and characterization of Streptococcus pyogenes superantigen (Spe-C). Baghdad Science Journal. 2011. Vol. 8, no. 4, pp.956-961.
https://search.emarefa.net/detail/BIM-353669
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 960-961
Record ID
BIM-353669
