Study the effect of rifampicin in the level of thyroid's gland hormones and thyroid-stimulating hormone in rabbits
Other Title(s)
دراسة تأثير عقار الريفامبيسين في مستوى هرمونات الغدة الدرقية و الهرمون المحفز للدرقية في الأرنب
Author
Source
Ibn al-Haitham Journal for Pure and Applied Science
Issue
Vol. 22, Issue 3 (30 Sep. 2009)8 p.
Publisher
University of Baghdad College of Education for Pure Science / Ibn al-Haitham
Publication Date
2009-09-30
Country of Publication
Iraq
No. of Pages
8
Main Subjects
Topics
Abstract EN
The aim of this study was intended to study the effect of rifampicin in the level of thyroid's gland hormones (T4 ،T3) and thyroid -stimulating hormone (TSH) in rabbits.
Eight male rabbits were used through out this study, their weights were measured before the starting of the experiment.
Animals were divided into two groups (each group contains 4 rabbits), the first group was administrated daily with 15 mg/Kg physiological normal saline for 35 days and used as a control group, while the second group was administrated with 15 mg /Kg daily for 35 day of rifampicin capsule 300 mg.
At the end of the experiment, all of animal groups were weighted and the sera was prepared to measure the hormones.
The results showed that there was a significant decrease (P < 0.05) in the mean of animals weights in the second group that was treated with rifampicin in comparison with the control group.
A significant increase (P < 0.05)was in T4, and T3 hormones level, and a significant decrease (P < 0.05)was in TSH hormone level in the second group that treated with rifampicin in comparison with the control group.
From this study, can conclude that rifampicin has a negative effect on thyroid gland function which might disorder on the secretion activity of thyroid gland hormones.
American Psychological Association (APA)
Sabri, Daliya Abd al-Latif. 2009. Study the effect of rifampicin in the level of thyroid's gland hormones and thyroid-stimulating hormone in rabbits. Ibn al-Haitham Journal for Pure and Applied Science،Vol. 22, no. 3.
https://search.emarefa.net/detail/BIM-354603
Modern Language Association (MLA)
Sabri, Daliya Abd al-Latif. Study the effect of rifampicin in the level of thyroid's gland hormones and thyroid-stimulating hormone in rabbits. Ibn al-Haitham Journal for Pure and Applied Science Vol. 22, no. 3 (2009).
https://search.emarefa.net/detail/BIM-354603
American Medical Association (AMA)
Sabri, Daliya Abd al-Latif. Study the effect of rifampicin in the level of thyroid's gland hormones and thyroid-stimulating hormone in rabbits. Ibn al-Haitham Journal for Pure and Applied Science. 2009. Vol. 22, no. 3.
https://search.emarefa.net/detail/BIM-354603
Data Type
Journal Articles
Language
English
Notes
Includes appendices.
Record ID
BIM-354603