In vivo study of compounds 3-(acetyl alicyloyl)‎-5, 6-oisopropylidene-l-ascorbic acid, 2, 3- (acetyl salicyloyl)‎-5, 6–o-isopropylidene-l-ascorbic acid and 2, 3, 5, 6-tetra(acetyl salicyloyl)‎-l-ascorbic acid

Abstract EN

In vivo study was made for the coumpounds 3-(ocetyl Salicyloyl)-5,6-O-isoprpy lidene- L-ascorbicocid,2,3-(acetyl Salicyloyl )-5,6-o- isopropylidene-L-ascorbic acid and 2,3,5,6- (acetyl Salicyloyl )-L- ascorbic acid .And a measurement was mod for the concentration of the liberated aspirin in blood samples a fter (2,3,4,6,8,10) hours of the initial dose for the animal .The results showed that the highest concentration of aspirin was after four hours of giving the dose to the animal which is in accordance with pharmacokinetics studies