Estimation of ceruloplasmin activity, and copper, iron levels in sera of normal pregnants

Abstract EN

This study was undertaken to shed light on the changes of levels of C'P activity, Cu and Fe in sera of (53) normal non-smoker pregnants without complication, during three trimesters of pregnancy.

include (1$) pregnants in the الال trimester, G2 (19) pregnants wear taken in the أ'ئ trimester and G3 (16) pregnants ٢١؛ the 3 trimester.

Another (18) serum samples were taken from healthy non-pregnant women age matched as control group G4.

Results showed a significant steady elevation in أ’? aetivity and serum Cu with advanced trimester of pregnancy compared to control.

The iron concentrations in the sera of pregnant women showed a significant reduction compared to control group also a steady decrease in Fe levels with advanced trimester was ؛’our،d.

The increased activities in CP as endogenous antioxidant during advanced pregnancy could be acountcr balance to the free radical generation due to the increase in Cu concentration with advance gestation.