Disturbance of some coagulation and fibrinolytic factors in essential hypertension
Other Title(s)
اضطراب بعض عوامل التجلط و تحلل الفيبرين في مرضى ارتفاع ضغط الدم الأولي
Joint Authors
Abd al-Qadir, Samir Sayyid
Ahmad, Marwah Abd al-Aziz
Muhammad, Mustafa Jabir
Awad, Afat Muhammad Abd al-Munim
Source
Issue
Vol. 30, Issue 3 (30 Sep. 2006), pp.97-108, 12 p.
Publisher
Assiut University Faculty of Medicine
Publication Date
2006-09-30
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Topics
Abstract EN
Background: Hypertension is an established risk factor for acute coronary events.
Growing evidence is now apparent that hypertension is accompanied by hypercoagulable and/ or hypofibrinoltic state , both of which can be the cause of several cardiovascular risk factors noticed with hypertension Aim of the work: To show the relationship between hypertension' and some components of fibrinolytic and coagulation systems .
In this study, the plasma levels of fibrinogen, FVII , D-dimer, t-PA and PAI-1 were studied in three groups of male persons.
Methods: A hypertensive group of patients (16), complicated hypertensive group (16) and a group of normotensive persons (16) were included in this work.
Patients were selected from outpatient clinic of Cardiology Department, Assiut University Hospital, during the period from December 2001 until December 2002.
Results: The mean plasma levels of fibrinogen, FVII, t-PA , PAI-1 and D dimer before treatment of the hypertensive and complicated hypertensive groups were significantly higher than that of the normotensive group .The mean plasma levels of these factors (except FVII) in the complicated hypertensive group were significantly higher than that of the hypertensive group.
After treatment of these groups, the mean plasma levels of all factors decreased significantly and there was no significant difference between the two groups.
Conclusion: It is clear from this study that there are disturbances in the levels of coagulation and fibrinolytic factors in hypertensive patients particulary in the complicated hypertensive patients.
This indicates severity of disturbance of these factors in hypertensive patients making them risk factors for the development of coronary heart disease, myocardial infarction, unstable angina, etc.
American Psychological Association (APA)
Muhammad, Mustafa Jabir& Abd al-Qadir, Samir Sayyid& Awad, Afat Muhammad Abd al-Munim& Ahmad, Marwah Abd al-Aziz. 2006. Disturbance of some coagulation and fibrinolytic factors in essential hypertension. Assiut Medical Journal،Vol. 30, no. 3, pp.97-108.
https://search.emarefa.net/detail/BIM-35640
Modern Language Association (MLA)
Muhammad, Mustafa Jabir…[et al.]. Disturbance of some coagulation and fibrinolytic factors in essential hypertension. Assiut Medical Journal Vol. 30, no. 3 (Sep. 2006), pp.97-108.
https://search.emarefa.net/detail/BIM-35640
American Medical Association (AMA)
Muhammad, Mustafa Jabir& Abd al-Qadir, Samir Sayyid& Awad, Afat Muhammad Abd al-Munim& Ahmad, Marwah Abd al-Aziz. Disturbance of some coagulation and fibrinolytic factors in essential hypertension. Assiut Medical Journal. 2006. Vol. 30, no. 3, pp.97-108.
https://search.emarefa.net/detail/BIM-35640
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 106-107
Record ID
BIM-35640