Determination of magnesium, zinc, and reduced glutathione levels in serum of asthmatic patients

Abstract EN

Asthma is a disease characterized by hyper reactivity of the trachca and bronchi to reversible cither spontaneously or as a result of treatment in thisstudy serum magnesium.

Zinc, and reduced glutathione levels were measured in order to determine their levels in the asthmatic patients and comparing these level with the healthy controls.

as four asthmatic paùcms were enrolled in the study and their pulmonary function test, and the levels ofMg.Zn, and GSH.

Scrum magnesium and scrum zinc were determined by using Atomic Absorption spectrophotometer .

While serum glutathione was determined by spectrophotometric analysis.

The asthmatic patients wen.* divided into four groups according to the interpretation of the pulmonary function test : severe expiratory flow' )imitation, moderate expiratory flow limitation , slight expiratory flow limitation and normal lung values.

٨١ this study, it was found that serum magnesium levels in severe eases of asthmatic patients were significantly lower titan the health) control population [0.92 i 0.1?mmol / L vs.

1.

01 ± 0.

19 mmol / L ; (p < 0.

05 ) while the other cases did not show' any significant differences compared with the health)' control .

for serum zic levels, it W'as found that the slight eases of asthmatic patients were significantly higher than the healthy control [ 19.48 ± 1.93 م mol / L '17.

01± 2094 ± mol / l.(P < 0.

05 )].

however, the other cases did not shtnv any significant différences compared with healthy control.

While scrum glutathione levels in severe and slight cases of astluiiatic patienLs were lower than the healthy control .

[2.

08 ± 0.

05]