Acute renal failure and severe thrombocytopenia associated with metamizole
Joint Authors
Redondo-Pachon, Maria Dolores
Enriquez, Ricardo
Sirvent, Ana Esther
Millan, Isabel
Romero, Alberto
Amoros, Francisco
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 25, Issue 1 (28 Feb. 2014), pp.121-125, 5 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2014-02-28
Country of Publication
Saudi Arabia
No. of Pages
5
Main Subjects
Topics
Abstract EN
Metamizole or dipyrone is a pyrazolone derivative that belongs to the non-steroidal anti-inflammatory drugs.
Its main side-effect is hematological toxicity.
Thrombocytopenia due to metamizole is rare and is usually associated with the involvement of the two other blood series.
Drug-induced thrombocytopenia is more frequently related to immune mechanisms, and the diagnosis is still largely made by exclusion of other causes and by correlation of timing of thrombocytopenia with the administration of drug.
Metamizole may cause acute renal failure due to hemodynamic renal failure/acute tubular necrosis and/or acute tubulointerstitial nephritis.
We report a case of acute renal failure and severe thrombocytopenia after metamizole.
As far as we know, this combination of adverse effects from this drug has not been reported previously.
American Psychological Association (APA)
Redondo-Pachon, Maria Dolores& Enriquez, Ricardo& Sirvent, Ana Esther& Millan, Isabel& Romero, Alberto& Amoros, Francisco. 2014. Acute renal failure and severe thrombocytopenia associated with metamizole. Saudi Journal of Kidney Diseases and Transplantation،Vol. 25, no. 1, pp.121-125.
https://search.emarefa.net/detail/BIM-356992
Modern Language Association (MLA)
Redondo-Pachon, Maria Dolores…[et al.]. Acute renal failure and severe thrombocytopenia associated with metamizole. Saudi Journal of Kidney Diseases and Transplantation Vol. 25, no. 1 (Jan. / Feb. 2014), pp.121-125.
https://search.emarefa.net/detail/BIM-356992
American Medical Association (AMA)
Redondo-Pachon, Maria Dolores& Enriquez, Ricardo& Sirvent, Ana Esther& Millan, Isabel& Romero, Alberto& Amoros, Francisco. Acute renal failure and severe thrombocytopenia associated with metamizole. Saudi Journal of Kidney Diseases and Transplantation. 2014. Vol. 25, no. 1, pp.121-125.
https://search.emarefa.net/detail/BIM-356992
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 124-125
Record ID
BIM-356992