Tranexamic acid overdosage-induced generalized seizure in renal failure
Joint Authors
Agarwal, Sanjay K.
Bhat, Anil
Vibha, Deepti
Dogra, Manu
Bhowmik, Dipankar M.
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 25, Issue 1 (28 Feb. 2014), pp.130-132, 3 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2014-02-28
Country of Publication
Saudi Arabia
No. of Pages
3
Main Subjects
Topics
- Islamic jurisprudence
- Social participation
- Addiction
- Drugs
- Therapeutics
- Overdoses
- Narcotics drugs
- Poisoning
- Kidney failure
- Tranexamic acid
Abstract EN
We report a 45-year-old lady with chronic kidney disease stage 4 due to chronic tubulointerstial disease.
She was admitted to our center for severe anemia due to menorrhagia and deterioration of renal function.
She was infused three units of packed cells during a session of hemodialysis.
Tranexamic acid (TNA) 1 g 8-hourly was administered to her to control bleeding per vaginum.
Two hours after the sixth dose of TNA, she had an episode of generalized tonic clonic convulsions.
TNA was discontinued.
Investigations of the patient revealed no biochemical or structural central nervous system abnormalities that could have provoked the convulsions.
She did not require any further dialytic support.
She had no further episodes of convulsion till discharge and during the two months of follow-up.
Thus, the precipitating cause of convulsions was believed to be an overdose of TNA.
American Psychological Association (APA)
Bhat, Anil& Bhowmik, Dipankar M.& Vibha, Deepti& Dogra, Manu& Agarwal, Sanjay K.. 2014. Tranexamic acid overdosage-induced generalized seizure in renal failure. Saudi Journal of Kidney Diseases and Transplantation،Vol. 25, no. 1, pp.130-132.
https://search.emarefa.net/detail/BIM-357015
Modern Language Association (MLA)
Bhat, Anil…[et al.]. Tranexamic acid overdosage-induced generalized seizure in renal failure. Saudi Journal of Kidney Diseases and Transplantation Vol. 25, no. 1 (Jan. / Feb. 2014), pp.130-132.
https://search.emarefa.net/detail/BIM-357015
American Medical Association (AMA)
Bhat, Anil& Bhowmik, Dipankar M.& Vibha, Deepti& Dogra, Manu& Agarwal, Sanjay K.. Tranexamic acid overdosage-induced generalized seizure in renal failure. Saudi Journal of Kidney Diseases and Transplantation. 2014. Vol. 25, no. 1, pp.130-132.
https://search.emarefa.net/detail/BIM-357015
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 132
Record ID
BIM-357015