Histological alterations and biochemical changes in the liver of sheep following Echis coloratus envenomation
Author
Source
Saudi Journal of Biological Sciences
Issue
Vol. 18, Issue 2 (30 Jun. 2011), pp.169-174, 6 p.
Publisher
Publication Date
2011-06-30
Country of Publication
Saudi Arabia
No. of Pages
6
Main Subjects
Topics
Abstract EN
Snake envenoming is a major problem in Al-Jouf Province of Saudi Arabia where most of these envenoming are caused by Echis coloratus which is the highest risk to human and animals in this Province.
Little, if any, has been carried out on the histological alterations and biochemical changes in the liver of sheep following snake envenomation.
Healthy adult male Ovis orientalis sheep were subjected to E.
coloratus envenomation in an attempt to evaluate the histological alterations and biochemical changes in the liver.
E.
coloratus venom elevated glucose, aspartate aminotransferase (AST), alanine aminotransferase (ALT), triglyceride and total bilirubin while cholesterol was reduced.
The histological alterations were mainly pyknosis, karyorrhexis, cytoplasmic vacuolation, necrosis, fatty changes and hepatocytes atrophy.
Sinusoidal dilatation, Kupffer cell activation, amyloidosis, portal vein thrombosis, partial glycogen depletion and hepatic architecture distortion were also detected.
The findings revealed that E.
coloratus venom produced biochemical changes and histological alterations in the liver of the envenomated sheep that might affect the functions of this organ severely.
American Psychological Association (APA)
Jarrar, Bashir M.. 2011. Histological alterations and biochemical changes in the liver of sheep following Echis coloratus envenomation. Saudi Journal of Biological Sciences،Vol. 18, no. 2, pp.169-174.
https://search.emarefa.net/detail/BIM-357603
Modern Language Association (MLA)
Jarrar, Bashir M.. Histological alterations and biochemical changes in the liver of sheep following Echis coloratus envenomation. Saudi Journal of Biological Sciences Vol. 18, no. 2 (2011), pp.169-174.
https://search.emarefa.net/detail/BIM-357603
American Medical Association (AMA)
Jarrar, Bashir M.. Histological alterations and biochemical changes in the liver of sheep following Echis coloratus envenomation. Saudi Journal of Biological Sciences. 2011. Vol. 18, no. 2, pp.169-174.
https://search.emarefa.net/detail/BIM-357603
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 173-174
Record ID
BIM-357603