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Thiocyclam does not induce structural chromosome aberrations in human lymphocytes in vitro
Joint Authors
Salih, Kamil
Sarhan, Muhammad A. A.
Celikler, Sirap
Source
Saudi Journal of Biological Sciences
Issue
Vol. 17, Issue 3 (31 Jul. 2010), pp.215-217, 3 p.
Publisher
Publication Date
2010-07-31
Country of Publication
Saudi Arabia
No. of Pages
3
Main Subjects
Topics
Abstract EN
Thiocyclam (trade name Evisect) is a broad-spectrum nereistoxin analogue insecticide used widely for agricultural applications.
The aim of this investigation was to determine its genotoxic effects in the chromosome aberration (CA) test and determining of mitotic index (MI), using lymphocytes from peripheral blood samples of healthy human donors.
A negative and a positive control (MMC) were also included.
Chromosomal analyses of the metaphase plates of the samples treated with 14 different concentrations (from 0.1 to 120 lg / ml) of thiocyclam, indicating the lack effect on chromosomes.
Thus thiocyclam is not genotoxic but highly toxic on cell proliferation in human lymphocytes.
American Psychological Association (APA)
Celikler, Sirap& Salih, Kamil& Sarhan, Muhammad A. A.. 2010. Thiocyclam does not induce structural chromosome aberrations in human lymphocytes in vitro. Saudi Journal of Biological Sciences،Vol. 17, no. 3, pp.215-217.
https://search.emarefa.net/detail/BIM-357801
Modern Language Association (MLA)
Celikler, Sirap…[et al.]. Thiocyclam does not induce structural chromosome aberrations in human lymphocytes in vitro. Saudi Journal of Biological Sciences Vol. 17, no. 3 (Jul. 2010), pp.215-217.
https://search.emarefa.net/detail/BIM-357801
American Medical Association (AMA)
Celikler, Sirap& Salih, Kamil& Sarhan, Muhammad A. A.. Thiocyclam does not induce structural chromosome aberrations in human lymphocytes in vitro. Saudi Journal of Biological Sciences. 2010. Vol. 17, no. 3, pp.215-217.
https://search.emarefa.net/detail/BIM-357801
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 217
Record ID
BIM-357801