Investigation on plasmodium falciparum and plasmodium vivax infection influencing host haematological factors in tribal dominant and malaria endemic population of jharkhand

Abstract EN

The study was undertaken to elucidate the association of host haematological and biochemical indices in Plasmodium falciparum and Plasmodium vivax malaria in order to explore whether these parameters are unique to disease or act as a potential diagnostic marker.

Haematological and biochemical parameters in 106 malarial patients and 33 healthy subjects were evaluated.

Following parameters were significantly lower in all infection types (P.

vivax, P.

falciparum and mixed infection); haemoglobin, blood sugar, PCV and blood urea, while ESR is significantly higher in all types of infection whereas serum bilirubin and creatinine are significantly higher except mixed and vivax infection, respectively.

Interestingly, parasitaemia, temperature and age are significantly correlated with blood urea, blood sugar and ESR respectively in vivax infection whereas parasitaemia with PCV and blood sugar and age with PCV in falciparum infection.

Malaria infected subjects exhibited alterations in some haematological parameters with low haemoglobin, blood sugar and PCV whereas elevated ESR and serum bilirubin being the important findings observed in our study.

These evaluations could be considered to be reliable clinical and * Corresponding author.

Tel.: +91 9934190987.

E-mail addresses: mobassir.novel@gmail.com (M.M.

Hussain), soh.khan@gmail.com (M.

Sohail), abhi.biotech@gmail.com (K.

Abhishek), mrazi.vbu@gmail.com (M.

Raziuddin).

Peer review under responsibility of King Saud University.