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Study of the pituitary-gonadal axis in the proestrus phase in adult female rats subjected to social isolation
Author
Source
Journal of the Arab Society for Medical Research
Issue
Vol. 7, Issue 2 (31 Dec. 2012), pp.86-91, 6 p.
Publisher
Arab Society for Medical Research
Publication Date
2012-12-31
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Social isolation is a type of stress that might adversely affect sex cycles in both animals and humans.
The present study was planned to investigate the pituitary–gonadal axis in the proestrus phase of estrous cycle in adult female rats subjected to social isolation stress for 8 weeks.
Materials and methods Twenty Sprague–Dawley adult female rats were divided into two experimental groups : a control group (n = 10) and a socially isolated group (SI, n = 10).
Throughout the study, all rats were monitored for body weight and food intake.
After 8 weeks, rats were sacrificed in the proestrus phase of estrous cycle.
All rats were examined for final body weight, rectal temperature, hematocrit value, and serum levels of follicle stimulating hormone, luteinizing hormones, prolactin hormone, 17-b estradiol, and progesterone in addition to histological examination of the ovaries.
Results The results of the present study showed that the SI group had significant decrease in their final body weights and their serum levels of 17-b estradiol and progesterone, whereas the serum level of prolactin was significantly increased.
Histological examination of SI rat ovaries showed fewer growing ovarian follicles and numerous atretic ones compared to control rat ovaries.
Conclusion These findings indicate that social isolation might result in depressed ovarian function in adult female rats.
American Psychological Association (APA)
Bahjat, Nahhal M.. 2012. Study of the pituitary-gonadal axis in the proestrus phase in adult female rats subjected to social isolation. Journal of the Arab Society for Medical Research،Vol. 7, no. 2, pp.86-91.
https://search.emarefa.net/detail/BIM-359078
Modern Language Association (MLA)
Bahjat, Nahhal M.. Study of the pituitary-gonadal axis in the proestrus phase in adult female rats subjected to social isolation. Journal of the Arab Society for Medical Research Vol. 7, no. 2 (2012), pp.86-91.
https://search.emarefa.net/detail/BIM-359078
American Medical Association (AMA)
Bahjat, Nahhal M.. Study of the pituitary-gonadal axis in the proestrus phase in adult female rats subjected to social isolation. Journal of the Arab Society for Medical Research. 2012. Vol. 7, no. 2, pp.86-91.
https://search.emarefa.net/detail/BIM-359078
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 60-91
Record ID
BIM-359078