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Possible recovery from an acute envenomation in male rats with LD50 of Echis coloratus crude venom : I-A seven days hematological follow-up study
Joint Authors
al-Sadun, Muhammad K.
Fahim, Asim
Source
Saudi Journal of Biological Sciences
Issue
Vol. 19, Issue 2 (30 Jun. 2012), pp.221-227, 7 p.
Publisher
Publication Date
2012-06-30
Country of Publication
Saudi Arabia
No. of Pages
7
Main Subjects
Topics
Abstract EN
The effect of an acute LD50 dose of Echis coloratus crude venom in male albino rats was tested on blood parameters: white blood cells (WBCs), red blood cells (RBCs), platelets count, hemoglobin, hematocrit, mean cell volume (MCV), mean cell hemoglobin (MCH) and mean cell hemoglobin concentration (MCHC), also serum glucose, total protein, triglycerides with alanine transaminase (ALT), aspartate transaminase (AST), alkaline phosphatase (ALP) and c-glutamyl transferase (GGT) enzyme activities.
The effect of the LD50 dose was monitored over a period of seven days, with time intervals of 1, 3, 6, 12, 24, 72 h.
All of the tested parameters show fluctuations with time and with tendency to regain normal control level after 12 h.
At 12–24 h it seems to be crucial for the process of physiological recovery, in spite of the irreversible damage and tissue distraction.
The process of physiological adaptation and recovery from the lethal destructive venom effect seems to stabilize after one week, leaving the animal alive with several biochemical altered metabolisms and disturbed physiological profile.
American Psychological Association (APA)
al-Sadun, Muhammad K.& Fahim, Asim. 2012. Possible recovery from an acute envenomation in male rats with LD50 of Echis coloratus crude venom : I-A seven days hematological follow-up study. Saudi Journal of Biological Sciences،Vol. 19, no. 2, pp.221-227.
https://search.emarefa.net/detail/BIM-359689
Modern Language Association (MLA)
al-Sadun, Muhammad K.& Fahim, Asim. Possible recovery from an acute envenomation in male rats with LD50 of Echis coloratus crude venom : I-A seven days hematological follow-up study. Saudi Journal of Biological Sciences Vol. 19, no. 2 (2012), pp.221-227.
https://search.emarefa.net/detail/BIM-359689
American Medical Association (AMA)
al-Sadun, Muhammad K.& Fahim, Asim. Possible recovery from an acute envenomation in male rats with LD50 of Echis coloratus crude venom : I-A seven days hematological follow-up study. Saudi Journal of Biological Sciences. 2012. Vol. 19, no. 2, pp.221-227.
https://search.emarefa.net/detail/BIM-359689
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 226-227
Record ID
BIM-359689