Acute exposure to Catha edulis depresses contractility and induces myocardial infarction in spontaneously contracting, isolated rabbit’s heart
Joint Authors
al-Umari, Hasan Said
al-Khatib, Mahmud
al-Hashim, Fahd H.
Dallak, Muhammad A.
Nui, Luqa O.
Ibn Jaliah, Ismail M.
Rizq, Mahmud H.
Saqr, Husayn F.
Shatur, Abd Allah S.
Source
Saudi Journal of Biological Sciences
Issue
Vol. 19, Issue 1 (31 Mar. 2012), pp.93-101, 9 p.
Publisher
Publication Date
2012-03-31
Country of Publication
Saudi Arabia
No. of Pages
9
Main Subjects
Topics
Abstract EN
Khat chewing is a recreational habit known to pose major socio-economic and medical problems in countries of Southern Arabia and the Horn of Africa.
Among other adverse health effects, khat chewing has been associated with an increased risk of myocardial infarction (MI) in heavy consumers.
This study was carried out to examine the direct effects of Catha edulis extract on contractility of spontaneously contracting, isolated rabbit heart and to investigate its mechanism of action.
Isolated six rabbit’s hearts attached to a Langendorff apparatus were perfused with extract at a constant flow rate and continuously bubbled with a 95% O2/5% CO2 gas mixture.
Each heart served as its own control, as responses were recorded before and after administration of
American Psychological Association (APA)
al-Hashim, Fahd H.& Dallak, Muhammad A.& Nui, Luqa O.& Ibn Jaliah, Ismail M.& al-Umari, Hasan Said& Rizq, Mahmud H.…[et al.]. 2012. Acute exposure to Catha edulis depresses contractility and induces myocardial infarction in spontaneously contracting, isolated rabbit’s heart. Saudi Journal of Biological Sciences،Vol. 19, no. 1, pp.93-101.
https://search.emarefa.net/detail/BIM-359978
Modern Language Association (MLA)
al-Hashim, Fahd H.…[et al.]. Acute exposure to Catha edulis depresses contractility and induces myocardial infarction in spontaneously contracting, isolated rabbit’s heart. Saudi Journal of Biological Sciences Vol. 19, no. 1 (2012), pp.93-101.
https://search.emarefa.net/detail/BIM-359978
American Medical Association (AMA)
al-Hashim, Fahd H.& Dallak, Muhammad A.& Nui, Luqa O.& Ibn Jaliah, Ismail M.& al-Umari, Hasan Said& Rizq, Mahmud H.…[et al.]. Acute exposure to Catha edulis depresses contractility and induces myocardial infarction in spontaneously contracting, isolated rabbit’s heart. Saudi Journal of Biological Sciences. 2012. Vol. 19, no. 1, pp.93-101.
https://search.emarefa.net/detail/BIM-359978
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 100-101
Record ID
BIM-359978